I'm personally hoping for characters more along the lines of Aliens or Alien 3, characters which are actually interesting & not just "cannon fodder" (although admittedly, a couple of the inmate characters in Alien 3 seemed as though they were.)
For the movie to truly be a success, it needs to be more than just great fight sequences & creature effects, the human characters need to play an integral role in the film, & must be able to captivate viewers to the point where the movie is viewed as more than just another "Vs" film, & rather as a serious piece in the Alien/Predator universe.